PATHELEN Hybrid an innovation in modern wound care
A new and innovative wound treatment!
PATHELEN® Hybrid is a combination of active ingredients cosisting of various fumed silica which efficiently eliminate biofilms and multi-resistant germs by physically removing them out of the wound.
The burden on the health system caused by chronic wounds.
The most common chronic wounds include leg ulcers, diabetic foot syndrome and pressure sores. In addition to the considerable costs of the respective standard treatment, these wounds are usually infected with germs that require the additional use of antibiotics.
According to the WHO, 25’000 people die each year in Europe from infections with multi-resistant pathogens. Treating patients with multi-resistant pathogens costs the European Union around € 1.5 billion anually. One reason for the growing resistance to antibiotics is the increased consumtion of antibiotics worldwide. Globally, it has increased by 36 percent between 2000 and 2011.
Antibiotics in Wound Care
Since 2011, western countries like Germany have been advocating a systematic reduction in the use of antibiotics. In Germany a S3 guideline on the rational use of antibiotcs has been in place since December 2013. In the treatment of chronic wounds, the local application of antibiotics can lead to the development of polyvalent contact allergies, the formation of resistance and thus a desisive disturbance of wound healing.
Systemic antibiotic therapy is only indivated if MRSA is detected and a wound infection is presend. Reserve antibiotics are used for this purpose.
Biofilm in chronic wounds
Biofilm is a complex microbial community in bacteria and fungi that forms a viscous matrix of sugar and proteins to protect against external threats. 60 to 90% of all chronic wounds have a biofilm.
Biofilms stimulate a chronix inflammatory reaction as the bodys immune response thereby impede wound healing. The resulting increase in wound exudation helps the biofilm to improve its nutritional situation. The biofilm is therefore better able to establish itself in the wound. To date, there is no one-step solution to eliminate biofilms.